Effect of an Immunosuppressive Agent, Cyclophosphamide, on Chronic Lactic Dehydrogenase Virus Viremia of Mice

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Effect of an immunosuppressive agent, cyclophosphamide, on chronic lactic dehydrogenase virus viremia of mice.

The immunosuppressive drug cyclophosphamide was used to study the effect of immunosuppression on the degree of chronic lactic dehydrogenase virus (LDV) viremia in mice. Weekly injections of cyclophosphamide caused an increase of LDV viremia of ca. 2.5 log(10) 50% infectious doses per ml as compared to the viremia in the nontreated mice. This increase occurred at about the same time that the for...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1971

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.4.6.720-724.1971